Thyroid Hormone Promotes Postnatal Rat Pancreatic β-Cell Development and Glucose-Responsive Insulin Secretion Through MAFA

Neonatal β cells do not secrete glucose-responsive insulin and are considered immature. We previously showed the transcription factor MAFA is key for the functional maturation of β cells, but the physiological regulators of this process are unknown. Here we show that postnatal rat β cells express th...

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Main Authors: Aguayo-Mazzucato, Cristina, Zavacki, Ann Marie, Marinelarena, Alejandra, Hollister-Lock, Jennifer, El Khattabi, Ilham, Marsili, Alessandro, Weir, Gordon C., Sharma, Arun, Larsen, P. Reed, Bonner-Weir, Susan
格式: Artigo
語言:Inglês
出版: American Diabetes Association 2013
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636623/
https://ncbi.nlm.nih.gov/pubmed/23305647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0849
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