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Hyaluronic acid based self-assembling nanosystems for CD44 target mediated siRNA delivery to solid tumors
Anticancer therapeutics employing RNA interference mechanism holds promising potentials for sequence-specific silencing of target genes. However targeted delivery of siRNAs to tumor tissues and cells and more importantly, their intracellular release at sites of interest still remains a major challen...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3636539/ https://ncbi.nlm.nih.gov/pubmed/23410679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.01.077 |
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