Tyrosine phosphorylation of a c-Src-like protein is increased in membranes of CD4- CD8- T lymphocytes from lpr/lpr mice.

Mice homozygous for the autosomal recessive lpr gene have a disorder that results in autoimmunity and massive accumulation of T lymphocytes lacking CD4 and CD8 surface markers. These abnormal T cells exhibit constitutive tyrosine phosphorylation of a component of the CD3-T-cell receptor complex. We...

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Библиографические подробности
Главные авторы: Katagiri, T, Ting, J P, Dy, R, Prokop, C, Cohen, P, Earp, H S
Формат: Artigo
Язык:Inglês
Опубликовано: 1989
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC363642/
https://ncbi.nlm.nih.gov/pubmed/2557544
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