Inactivation of the CovR/S Virulence Regulator Impairs Infection in an Improved Murine Model of Streptococcus pyogenes Naso-Pharyngeal Infection

Streptococcus pyogenes is a leading cause of pharyngeal infection, with an estimated 616 million cases per year. The human nasopharynx represents the major reservoir for all S. pyogenes infection, including severe invasive disease. To investigate bacterial and host factors that influence S. pyogenes...

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Main Authors: Alam, Faraz M., Turner, Claire E., Smith, Ken, Wiles, Siouxsie, Sriskandan, Shiranee
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636223/
https://ncbi.nlm.nih.gov/pubmed/23637876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061655
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