Inactivation of the CovR/S Virulence Regulator Impairs Infection in an Improved Murine Model of Streptococcus pyogenes Naso-Pharyngeal Infection

Streptococcus pyogenes is a leading cause of pharyngeal infection, with an estimated 616 million cases per year. The human nasopharynx represents the major reservoir for all S. pyogenes infection, including severe invasive disease. To investigate bacterial and host factors that influence S. pyogenes...

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Autores principales: Alam, Faraz M., Turner, Claire E., Smith, Ken, Wiles, Siouxsie, Sriskandan, Shiranee
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636223/
https://ncbi.nlm.nih.gov/pubmed/23637876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061655
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