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Inactivation of the CovR/S Virulence Regulator Impairs Infection in an Improved Murine Model of Streptococcus pyogenes Naso-Pharyngeal Infection

Streptococcus pyogenes is a leading cause of pharyngeal infection, with an estimated 616 million cases per year. The human nasopharynx represents the major reservoir for all S. pyogenes infection, including severe invasive disease. To investigate bacterial and host factors that influence S. pyogenes...

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Detalhes bibliográficos
Main Authors: Alam, Faraz M., Turner, Claire E., Smith, Ken, Wiles, Siouxsie, Sriskandan, Shiranee
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636223/
https://ncbi.nlm.nih.gov/pubmed/23637876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061655
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