Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate

Several lines of evidence suggest that genome-wide association studies (GWAS) have the potential to explain more of the “missing heritability” of common complex phenotypes. However, reliable methods to identify a larger proportion of single nucleotide polymorphisms (SNPs) that impact disease risk ar...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Andreassen, Ole A., Thompson, Wesley K., Schork, Andrew J., Ripke, Stephan, Mattingsdal, Morten, Kelsoe, John R., Kendler, Kenneth S., O'Donovan, Michael C., Rujescu, Dan, Werge, Thomas, Sklar, Pamela, Roddey, J. Cooper, Chen, Chi-Hua, McEvoy, Linda, Desikan, Rahul S., Djurovic, Srdjan, Dale, Anders M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636100/
https://ncbi.nlm.nih.gov/pubmed/23637625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003455
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