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Use of a selectable marker regulated by alpha interferon to obtain mutations in the signaling pathway.

We have selected mutations in genes encoding components of the signaling pathway for alpha interferon (IFN-alpha) by using a specially constructed cell line. The upstream region of the IFN-regulated human gene 6-16 was fused to the Escherichia coli guanine phosphoribosyltransferase (gpt) gene and tr...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Pellegrini, S, John, J, Shearer, M, Kerr, I M, Stark, G R
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1989
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC363606/
https://ncbi.nlm.nih.gov/pubmed/2513475
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