No evidence for PALB2 methylation in high-grade serous ovarian cancer

BACKGROUND: High-grade serous ovarian cancers are a distinct histological subtype of ovarian cancer often characterised by a dysfunctional BRCA/Fanconi anaemia (BRCA/FA) pathway, which is critical to the homologous recombination DNA repair machinery. An impaired BRCA/FA pathway sensitises tumours to...

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Main Authors: Mikeska, Thomas, Alsop, Kathryn, Mitchell, Gillian, Bowtell, David DL, Dobrovic, Alexander
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Brief Communication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636006/
https://ncbi.nlm.nih.gov/pubmed/23587053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1757-2215-6-26
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