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Quantifying the contribution of chromatin dynamics to stochastic gene expression reveals long, locus-dependent periods between transcriptional bursts

BACKGROUND: A number of studies have established that stochasticity in gene expression may play an important role in many biological phenomena. This therefore calls for further investigations to identify the molecular mechanisms at stake, in order to understand and manipulate cell-to-cell variabilit...

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Autors principals: Viñuelas, José, Kaneko, Gaël, Coulon, Antoine, Vallin, Elodie, Morin, Valérie, Mejia-Pous, Camila, Kupiec, Jean-Jacques, Beslon, Guillaume, Gandrillon, Olivier
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635915/
https://ncbi.nlm.nih.gov/pubmed/23442824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-11-15
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