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Quantifying the contribution of chromatin dynamics to stochastic gene expression reveals long, locus-dependent periods between transcriptional bursts

BACKGROUND: A number of studies have established that stochasticity in gene expression may play an important role in many biological phenomena. This therefore calls for further investigations to identify the molecular mechanisms at stake, in order to understand and manipulate cell-to-cell variabilit...

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Detalhes bibliográficos
Main Authors: Viñuelas, José, Kaneko, Gaël, Coulon, Antoine, Vallin, Elodie, Morin, Valérie, Mejia-Pous, Camila, Kupiec, Jean-Jacques, Beslon, Guillaume, Gandrillon, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635915/
https://ncbi.nlm.nih.gov/pubmed/23442824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-11-15
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