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Growth factor induction by the adenovirus type 5 E1A 12S protein is required for immortalization of primary epithelial cells.

The 12S protein encoded by the adenovirus E1A region induces cellular DNA synthesis in and proliferation and immortalization of primary rat epithelial cells in the presence or absence of serum. It also induces the production of a growth factor(s) that stimulates epithelial cell proliferation. We hav...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Autores principales: Quinlan, M P, Whyte, P, Grodzicker, T
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 1988
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363551/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2974923/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.8.3191-3203.1988
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