Growth factor induction by the adenovirus type 5 E1A 12S protein is required for immortalization of primary epithelial cells.
The 12S protein encoded by the adenovirus E1A region induces cellular DNA synthesis in and proliferation and immortalization of primary rat epithelial cells in the presence or absence of serum. It also induces the production of a growth factor(s) that stimulates epithelial cell proliferation. We hav...
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| Publicado no: | Mol Cell Biol |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
1988
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363551/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2974923/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.8.3191-3203.1988 |
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