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PAK–PIX interactions regulate adhesion dynamics and membrane protrusion to control neurite outgrowth

The roles of P21-activated kinase (PAK) in the regulation of axon outgrowth downstream of extracellular matrix (ECM) proteins are poorly understood. Here we show that PAK1–3 and PIX are expressed in the developing spinal cord and differentially localize to point contacts and filopodial tips within m...

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Bibliografiske detaljer
Main Authors: Santiago-Medina, Miguel, Gregus, Kelly A., Gomez, Timothy M.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635460/
https://ncbi.nlm.nih.gov/pubmed/23321640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.112607
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