A dominant trifluoperazine resistance gene from Saccharomyces cerevisiae has homology with F0F1 ATP synthase and confers calcium-sensitive growth.
The antipsychotic drug trifluoperazine has been long considered a calmodulin inhibitor from in vitro studies but may function in vivo as a more general inhibitor by disturbing ion fluxes and altering the membrane potential. Resistance to trifluoperazine can arise in Saccharomyces cerevisiae cells by...
Αποθηκεύτηκε σε:
| Εκδόθηκε σε: | Mol Cell Biol |
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| Κύριοι συγγραφείς: | , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Taylor & Francis
1988
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363536/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2905423/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.8.3094-3103.1988 |
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