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Modification of Pax6 and Olig2 expression in adult hippocampal neurogenesis selectively induces stem cell fate and alters both neuronal and glial populations

The generation of new neurons in the mammalian hippocampus continues throughout life, and lineage progression is regulated by transcription factors, local cues and environmental influences. The ability to direct stem/progenitor cell fate in situ may have therapeutic potential. Using an in vivo retro...

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Detalhes bibliográficos
Main Authors: Klempin, Friederike, Marr, Robert, Peterson, Daniel A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635101/
https://ncbi.nlm.nih.gov/pubmed/22162276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1005
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