Impaired regeneration in LGMD2A supported by increased Pax7 positive satellite cell content and muscle specific microRNA dysregulation

INTRODUCTION: Recent in vitro studies suggest that CAPN3 deficiency leads initially to accelerated myofiber formation followed by depletion of satellite cells (SC). In normal muscle, upregulation of miR-1 and miR-206 facilitates transition from proliferating SCs to differentiating myogenic progenito...

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Bibliografski detalji
Glavni autori: Rosales, Xiomara Q., Malik, Vinod, Sneh, Amita, Chen, Lei, Lewis, Sarah, Kota, Janaiah, Gastier-Foster, Julie M., Astbury, Caroline, Pyatt, Rob, Reshmi, Shalini, Rodino-Klapac, Louise R., Clark, K. Reed, Mendell, Jerry R., Sahenk, Zarife
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634894/
https://ncbi.nlm.nih.gov/pubmed/23553538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mus.23669
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