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Vanillin Inhibits Translation and Induces Messenger Ribonucleoprotein (mRNP) Granule Formation in Saccharomyces cerevisiae: Application and Validation of High-Content, Image-Based Profiling

Vanillin, generated by acid hydrolysis of lignocellulose, acts as a potent inhibitor of the growth of the yeast Saccharomyces cerevisiae. Here, we investigated the cellular processes affected by vanillin using high-content, image-based profiling. Among 4,718 non-essential yeast deletion mutants, the...

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Detalhes bibliográficos
Main Authors: Iwaki, Aya, Ohnuki, Shinsuke, Suga, Yohei, Izawa, Shingo, Ohya, Yoshikazu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634847/
https://ncbi.nlm.nih.gov/pubmed/23637899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061748
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