A carregar...
piggyBac as a high-capacity transgenesis and gene-therapy vector in human cells and mice
The stable genomic integration and expression of a large transgene is a major hurdle in gene therapy. We show that the modified piggyBac (PB) transposon system can be used to introduce a 207 kb genomic DNA fragment containing the RORγ/γt locus into human cells and mice. PB-mediated transgenesis resu...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Limited
2013
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3634665/ https://ncbi.nlm.nih.gov/pubmed/23519027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.010827 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|