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Systematic binding analysis of the insulin gene transcription control region: insulin and immunoglobulin enhancers utilize similar transactivators.

The 5' regulatory region (-345 to +1) of the rat insulin I gene (Ins-I) was examined for binding to cellular factors with short oligodeoxynucleotide probes. Over 40 binding species were detected. The binding profiles were specific for each cell type studied. We characterized the factors binding two...

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Publicat a:Mol Cell Biol
Autors principals: Moss, L G, Moss, J B, Rutter, W J
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1988
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363464/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3043185/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.6.2620-2627.1988
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