Secretion of Glycosylated Pro-B-Type Natriuretic Peptide from Normal Cardiomyocytes

BACKGROUND: B-type natriuretic peptide (BNP), a key cardiac hormone in cardiorenal homeostasis, is produced as a 108 amino acid pro-hormone proBNP1-108. proBNP1-108 is converted to a biologically active peptide BNP1-32 and an inactive NT-proBNP1-76. The widely accepted model is that the normal heart...

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Main Authors: Tonne, Jason M., Campbell, Jarryd M., Cataliotti, Alessandro, Ohmine, Seiga, Thatava, Tayaramma, Sakuma, Toshie, Macheret, Fima, Huntley, Brenda K., Burnett, John C., Ikeda, Yasuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634583/
https://ncbi.nlm.nih.gov/pubmed/21482747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2010.157438
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