Unusual selection and peripheral homeostasis for immunoregulatory CD4(−) CD8(−) T cells

Immunoregulatory CD4(−) CD8(−) (double-negative; DN) T cells exhibit a unique antigen-specific mode of suppression, yet the ontogeny of DN T cells remains enigmatic. We have recently shown that 3A9 T-cell receptor (TCR) transgenic mice bear a high proportion of immunoregulatory 3A9 DN T cells, facil...

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Autors principals: Dugas, Véronique, Chabot-Roy, Geneviève, Beauchamp, Claudine, Guimont-Desrochers, Fanny, Hillhouse, Erin E, Liston, Adrian, Lesage, Sylvie
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2013
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634545/
https://ncbi.nlm.nih.gov/pubmed/23293940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12064
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