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SMAD regulatory networks construct a balanced immune system

A balanced immune response requires combating infectious assaults while striving to maintain quiescence towards the self. One of the central players in this process is the pleiotropic cytokine transforming growth factor-β (TGF-β), whose deficiency results in spontaneous systemic autoimmunity in mice...

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Bibliographic Details
Main Authors: Malhotra, Nidhi, Kang, Joonsoo
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634534/
https://ncbi.nlm.nih.gov/pubmed/23347175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12076
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