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Essential role of the electroneutral Na(+)–HCO(3)(−) cotransporter NBCn1 in murine duodenal acid–base balance and colonic mucus layer build-up in vivo
Duodenal epithelial cells need efficient defence strategies during gastric acidification of the lumen, while colonic mucosa counteracts damage by pathogens by building up a bacteria-free adherent mucus layer. Transport of HCO(3)(−) is considered crucial for duodenal defence against acid as well as f...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Science Inc
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3634528/ https://ncbi.nlm.nih.gov/pubmed/23401617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.247874 |
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