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Oxygen sensing and hypoxia signalling pathways in animals: the implications of physiology for cancer
Studies of regulation of the haematopoietic growth factor erythropoietin led to the unexpected discovery of a widespread system of direct oxygen sensing that regulates gene expression in animals. The oxygen-sensitive signal is generated by a series of non-haem Fe(II)- and 2-oxoglutarate-dependent di...
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| Glavni autor: | |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Blackwell Science Inc
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3634517/ https://ncbi.nlm.nih.gov/pubmed/23401619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.251470 |
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