Relationship among guanine nucleotide exchange, GTP hydrolysis, and transforming potential of mutated ras proteins.
The effect of a series of mutations on the transforming potential of normal human rasH has been compared with their effects on GTPase and guanine nucleotide exchange rates of p21. The mutation Val-146 resulted in partial activation of transforming potential which could be attributed to a greater tha...
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| Veröffentlicht in: | Mol Cell Biol |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
1988
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363447/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3043178/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.6.2472-2478.1988 |
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