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From Data towards Knowledge: Revealing the Architecture of Signaling Systems by Unifying Knowledge Mining and Data Mining of Systematic Perturbation Data

Genetic and pharmacological perturbation experiments, such as deleting a gene and monitoring gene expression responses, are powerful tools for studying cellular signal transduction pathways. However, it remains a challenge to automatically derive knowledge of a cellular signaling system at a concept...

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Detalhes bibliográficos
Main Authors: Lu, Songjian, Jin, Bo, Cowart, L. Ashley, Lu, Xinghua
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634064/
https://ncbi.nlm.nih.gov/pubmed/23637789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061134
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