Tyrosine Kinase Inhibitors Induce Down-Regulation of c-Kit by Targeting the ATP Pocket

The stem cell factor receptor (SCF) c-Kit plays a pivotal role in regulating cell proliferation and survival in many cell types. In particular, c-Kit is required for early amplification of erythroid progenitors, while it must disappear from cell surface for the cell entering the final steps of matur...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: D'allard, Diane, Gay, Julie, Descarpentries, Clotilde, Frisan, Emilie, Adam, Kevin, Verdier, Frederique, Floquet, Célia, Dubreuil, Patrice, Lacombe, Catherine, Fontenay, Michaela, Mayeux, Patrick, Kosmider, Olivier
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634048/
https://ncbi.nlm.nih.gov/pubmed/23637779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060961
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge