Immune-Complex Mimics as a Molecular Platform for Adjuvant-Free Vaccine Delivery

Protein-based vaccine development faces the difficult challenge of finding robust yet non-toxic adjuvants suitable for humans. Here, using a molecular engineering approach, we have developed a molecular platform for generating self-adjuvanting immunogens that do not depend on exogenous adjuvants for...

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Detalhes bibliográficos
Main Authors: Pepponi, Ilaria, Stylianou, Elena, van Dolleweerd, Craig, Diogo, Gil Reynolds, Paul, Matthew J., Drake, Pascal M. W., Ma, Julian K.-C., Reljic, Rajko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634044/
https://ncbi.nlm.nih.gov/pubmed/23637771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060855
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