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Cryptochrome 1 Overexpression Correlates with Tumor Progression and Poor Prognosis in Patients with Colorectal Cancer

BACKGROUND: Clock genes drive about 5–15% of genome-wide mRNA expression, and disruption of the circadian clock may deregulate the cell's normal biological functions. Cryptochrome 1 is a key regulator of the circadian feedback loop and plays an important role in organisms. The present study was...

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Hlavní autoři: Yu, Hongyan, Meng, Xiangqi, Wu, Jiangxue, Pan, Changchuan, Ying, Xiaofang, Zhou, Yi, Liu, Ranyi, Huang, Wenlin
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634012/
https://ncbi.nlm.nih.gov/pubmed/23626715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061679
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