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Transcriptional-translational regulatory circuit in Saccharomyces cerevisiae which involves the GCN4 transcriptional activator and the GCN2 protein kinase.

GCN4 protein mediates the transcriptional activation of amino acid biosynthetic genes in Saccharomyces cerevisiae by specifically binding to DNA sequences in their 5'-regulatory regions. GCN4 expression is regulated at the level of translation, with translational derepression occurring under conditi...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Roussou, I, Thireos, G, Hauge, B M
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1988
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363394/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3290651/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.5.2132-2139.1988
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