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Transcriptional-translational regulatory circuit in Saccharomyces cerevisiae which involves the GCN4 transcriptional activator and the GCN2 protein kinase.

GCN4 protein mediates the transcriptional activation of amino acid biosynthetic genes in Saccharomyces cerevisiae by specifically binding to DNA sequences in their 5'-regulatory regions. GCN4 expression is regulated at the level of translation, with translational derepression occurring under conditi...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Biol
Autori principali: Roussou, I, Thireos, G, Hauge, B M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 1988
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363394/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3290651/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.5.2132-2139.1988
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