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Anthrax Lethal Toxin Downregulates Claudin-5 Expression in Human Endothelial Tight Junctions
Vascular leakage pathologies such as pleural effusion and hemorrhage are hallmarks of anthrax pathogenesis. We previously reported that anthrax lethal toxin (LT), the major virulence factor of anthrax, reduces barrier function in cultured primary human microvascular endothelial cells. Here, we show...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2013
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3633853/ https://ncbi.nlm.nih.gov/pubmed/23626836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062576 |
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