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p67(phox) terminates the phospholipase A(2)-derived signal for activation of NADPH oxidase (NOX2)

The phospholipase A(2) (PLA(2))activity of phosphorylated peroxiredoxin 6 (Prdx6) is required for activation of NADPH oxidase (NOX2). We investigated the interaction of Prdx6 with p67(phox) and its effect on NOX2 activity. With the use of specific antibodies, coimmunoprecipitation of p67(phox) and p...

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Bibliografiske detaljer
Main Authors: Krishnaiah, Saikumari Y., Dodia, Chandra, Feinstein, Sheldon I., Fisher, Aron B.
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633811/
https://ncbi.nlm.nih.gov/pubmed/23401562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-222133
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