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Differential effects of serotonin-specific and excitotoxic lesions of OFC on conditioned reinforcer devaluation and extinction in rats

The orbitofrontal cortex (OFC) is critical for behavioral adaptation in response to changes in reward value. Here we investigated, in rats, the role of OFC and, specifically, serotonergic neurotransmission within OFC in a reinforcer devaluation task (which measures behavioral flexibility). This task...

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Bibliographische Detailangaben
Hauptverfasser: West, Elizabeth A., Forcelli, Patrick A., McCue, David L., Malkova, Ludise
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633724/
https://ncbi.nlm.nih.gov/pubmed/23458741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2013.02.027
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