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Differential effects of serotonin-specific and excitotoxic lesions of OFC on conditioned reinforcer devaluation and extinction in rats

The orbitofrontal cortex (OFC) is critical for behavioral adaptation in response to changes in reward value. Here we investigated, in rats, the role of OFC and, specifically, serotonergic neurotransmission within OFC in a reinforcer devaluation task (which measures behavioral flexibility). This task...

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Detalhes bibliográficos
Main Authors: West, Elizabeth A., Forcelli, Patrick A., McCue, David L., Malkova, Ludise
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633724/
https://ncbi.nlm.nih.gov/pubmed/23458741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2013.02.027
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