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Single-amino-acid substitutions within the signal sequence of yeast prepro-alpha-factor affect membrane translocation.

We used a genetic approach to identify point mutations in the signal sequence of a secreted eucaryotic protein, yeast alpha-factor. Signal sequence mutants were obtained by selecting for cells that partially mistargeted into mitochondria a fusion protein consisting of the alpha-factor signal sequenc...

詳細記述

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書誌詳細
出版年:Mol Cell Biol
主要な著者: Allison, D S, Young, E T
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 1988
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363369/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3290645/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.5.1915
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