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Single-amino-acid substitutions within the signal sequence of yeast prepro-alpha-factor affect membrane translocation.
We used a genetic approach to identify point mutations in the signal sequence of a secreted eucaryotic protein, yeast alpha-factor. Signal sequence mutants were obtained by selecting for cells that partially mistargeted into mitochondria a fusion protein consisting of the alpha-factor signal sequenc...
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| Publicado en: | Mol Cell Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis
1988
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363369/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3290645/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.5.1915 |
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