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Localization of a major receptor-binding domain for epidermal growth factor by affinity labeling.

Epidermal growth factor (EGF) receptor was affinity labeled with 125I-labeled EGF, using bifunctional covalent cross-linking agents. The affinity-labeled receptor was isolated and cleaved with CNBr to yield a single-labeled fragment, which was unequivocally identified by site-specific antibodies and...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Lax, I, Burgess, W H, Bellot, F, Ullrich, A, Schlessinger, J, Givol, D
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 1988
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363348/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3260004/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.4.1831-1834.1988
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