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Thiazolidinedione drugs block cardiac K(ATP) channels and may increase propensity for ischaemic ventricular fibrillation in pigs
AIMS/HYPOTHESIS: Opening of ATP-sensitive potassium (K(ATP)) channels during myocardial ischaemia shortens action potential duration and is believed to be an adaptive, energy-sparing response. Thiazolidinedione drugs block K(ATP) channels in non-cardiac cells in vitro. This study determined whether...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3633423/ https://ncbi.nlm.nih.gov/pubmed/18251006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-008-0924-0 |
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