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Disease-enhancing antibodies improve the efficacy of bacterial toxin-neutralizing antibodies

During infection, humoral immunity produces a polyclonal response with various immunoglobulins recognizing different epitopes within the microbe or toxin. Despite this diverse response, the biological activity of an antibody (Ab) is usually assessed by the action of a monoclonal population. We demon...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chow, Siu-Kei, Smith, Cameron, MacCarthy, Thomas, Pohl, Mary Ann, Bergman, Aviv, Casadevall, Arturo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633089/
https://ncbi.nlm.nih.gov/pubmed/23601104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2013.03.001
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