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Disease-enhancing antibodies improve the efficacy of bacterial toxin-neutralizing antibodies

During infection, humoral immunity produces a polyclonal response with various immunoglobulins recognizing different epitopes within the microbe or toxin. Despite this diverse response, the biological activity of an antibody (Ab) is usually assessed by the action of a monoclonal population. We demon...

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Main Authors: Chow, Siu-Kei, Smith, Cameron, MacCarthy, Thomas, Pohl, Mary Ann, Bergman, Aviv, Casadevall, Arturo
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633089/
https://ncbi.nlm.nih.gov/pubmed/23601104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2013.03.001
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