Purkinje Cell Ataxin-1 Modulates Climbing Fiber Synaptic Input in Developing and Adult Mouse Cerebellum

Previous studies indicate that while transgenic mice with ATXN1[30Q]-D776-induced disease share pathological features caused by ATXN1[82Q] having an expanded polyglutamine tract, they fail to manifest the age-related progressive neurodegeneration seen in spinocerebellar ataxia type 1. The shared fea...

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Main Authors: Ebner, Blake A., Ingram, Melissa A., Barnes, Justin A., Duvick, Lisa A., Frisch, Jill L., Clark, H. Brent, Zoghbi, Huda Y., Ebner, Timothy J., Orr, Harry T.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633086/
https://ncbi.nlm.nih.gov/pubmed/23536093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6311-11.2013
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