Glucocorticoid receptor-dependent inhibition of cellular proliferation in dexamethasone-resistant and hypersensitive rat hepatoma cell variants.

Exposure of the Fu5 rat hepatoma cell line to glucocorticoids, such as dexamethasone and hydrocortisone, suppressed the growth rate and final density of cells grown in the presence of serum. This hormonal effect was proportional to receptor occupancy and affinity and, in addition, the glucocorticoid...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Cook, P W, Swanson, K T, Edwards, C P, Firestone, G L
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1988
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363302/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3380086/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.4.1449-1459.1988
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