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Glucocorticoid receptor-dependent inhibition of cellular proliferation in dexamethasone-resistant and hypersensitive rat hepatoma cell variants.

Exposure of the Fu5 rat hepatoma cell line to glucocorticoids, such as dexamethasone and hydrocortisone, suppressed the growth rate and final density of cells grown in the presence of serum. This hormonal effect was proportional to receptor occupancy and affinity and, in addition, the glucocorticoid...

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Publicat a:Mol Cell Biol
Autors principals: Cook, P W, Swanson, K T, Edwards, C P, Firestone, G L
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1988
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363302/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3380086/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.4.1449-1459.1988
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