Targeting Mycobacterium tuberculosis and Other Microbial Pathogens Using Improved Synthetic Antibacterial Peptides

The lack of effective therapies for treating tuberculosis (TB) is a global health problem. While Mycobacterium tuberculosis is notoriously resistant to most available antibiotics, we identified synthetic short cationic antimicrobial peptides that were active at low micromolar concentrations (less th...

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Autors principals: Ramón-García, Santiago, Mikut, Ralf, Ng, Carol, Ruden, Serge, Volkmer, Rudolf, Reischl, Markus, Hilpert, Kai, Thompson, Charles J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
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Mechanisms of Action: Physiological Effects
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632949/
https://ncbi.nlm.nih.gov/pubmed/23478953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00175-13
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