Novel Combinations of Vancomycin plus Ceftaroline or Oxacillin against Methicillin-Resistant Vancomycin-Intermediate Staphylococcus aureus (VISA) and Heterogeneous VISA

We demonstrated a significant inverse correlation between vancomycin and beta-lactam susceptibilities in vancomycin-intermediate Staphylococcus aureus (VISA) and heterogeneous VISA (hVISA) isolates. Using time-kill assays, vancomycin plus oxacillin or ceftaroline was synergistic against 3 of 5 VISA...

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Bibliographische Detailangaben
Hauptverfasser: Werth, B. J., Vidaillac, C., Murray, K. P., Newton, K. L., Sakoulas, G., Nonejuie, P., Pogliano, J., Rybak, M. J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632910/
https://ncbi.nlm.nih.gov/pubmed/23422917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02354-12
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