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The Antimalarial Activities of Methylene Blue and the 1,4-Naphthoquinone 3-[4-(Trifluoromethyl)Benzyl]-Menadione Are Not Due to Inhibition of the Mitochondrial Electron Transport Chain

Methylene blue and a series of recently developed 1,4-naphthoquinones, including 3-[4-(substituted)benzyl]-menadiones, are potent antimalarial agents in vitro and in vivo. The activity of these structurally diverse compounds against the human malaria parasite Plasmodium falciparum might involve thei...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ehrhardt, Katharina, Davioud-Charvet, Elisabeth, Ke, Hangjun, Vaidya, Akhil B., Lanzer, Michael, Deponte, Marcel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632896/
https://ncbi.nlm.nih.gov/pubmed/23439633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02248-12
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