Activities of Systemically Administered Echinocandins against In Vivo Mature Candida albicans Biofilms Developed in a Rat Subcutaneous Model

This study addresses the effects of micafungin, caspofungin, and anidulafungin against Candida albicans biofilms developed in a subcutaneous catheter rat model system. Doses of 5, 10, and 30 mg/kg (of body weight)/day (the last only for micafungin) were given intravenously for 5, 7, and 10 days. All...

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Bibliographic Details
Main Authors: Kucharíková, Soňa, Sharma, Nidhi, Spriet, Isabel, Maertens, Johan, Van Dijck, Patrick, Lagrou, Katrien
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632894/
https://ncbi.nlm.nih.gov/pubmed/23403433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02288-12
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