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In Vivo Efficacy of Anidulafungin against Mature Candida albicans Biofilms in a Novel Rat Model of Catheter-Associated Candidiasis

The present study demonstrates the efficacy of anidulafungin on mature Candida albicans biofilms in vivo. One hundred fifty-seven catheter fragments challenged with C. albicans were implanted subcutaneously in rats. After formation of biofilms, rats were treated with daily intraperitoneal injections...

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Detalhes bibliográficos
Main Authors: Kucharíková, Soňa, Tournu, Hélène, Holtappels, Michelle, Van Dijck, Patrick, Lagrou, Katrien
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944565/
https://ncbi.nlm.nih.gov/pubmed/20660685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00697-10
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