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Role for DNA replication in beta-globin gene activation.

Transcriptional activation of the Xenopus laevis beta-globin gene requires the synergistic action of the simian virus 40 enhancer and DNA replication in DEAE-dextran-mediated HeLa cell transfections. Replication does not act through covalent modification of the template, since its requirement was no...

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Detalhes bibliográficos
Main Authors: Enver, T, Brewer, A C, Patient, R K
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC363276/
https://ncbi.nlm.nih.gov/pubmed/2835669
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