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Identification, Functional Characterization, and Pathobiological Significance of GLI1 Isoforms in Human Cancers
Glioma-associated oncogene homolog 1 (GLI1) is the nuclear mediator of Hedgehog signaling that activates gene transcription via its zinc finger DNA-binding and transactivation domains. GLI1 plays a critical role in several cellular processes, including embryonic development, tumorigenesis, and tumor...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3632646/ https://ncbi.nlm.nih.gov/pubmed/22391302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-394622-5.00006-7 |
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